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It grows when you’re happy, when you’re sad, while you’re snuggled up in your favorite chair watching 24. It grows regardless of age, sex, race, c

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

reed, it has no bias, it doesn’t care if you’re sick, penniless or in the midst of a major life crises. It never pities, shows neither compassion

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

nor remorse and doesn’t spare a thought for the bad day you just had. Like rust it doesn’t sleep, it doesn’t eat, it doesn’t have a conscience but

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

that’s okay, it’s not personal. Its appetite is never satisfied and it never stops growing.

Like a scene from the movie “The Blob”, debt interes

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

grows and snowballs over time, swelling your original credit card or loan debt to the point where all you end up paying each month is the interest

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

on the debt you owe.

Stuck in the Spin Cycle

Like being forever caught in a washing machine set on the “spin” cycle it’s hard to get anywhere wit

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

h your debt reduction when you only opt to pay the minimum amount, this keeps you in debt longer and for the most part only covers a good chunk of

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

the interest never mind the original amount you borrowed. The banks and credit card companies love you, in fact, that’s why they give the option, s

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

re it makes the amount you pay each month manageable but you remained trapped in that nasty debt cycle.

Light At the End of the Tunnel

Although p

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

aying the minimum keeps the debt collector monkeys off your back you’re actually penalizing yourself by paying more in the long run. Do the simple

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

thing of increasing the amount you pay or pay more frequently, doing so puts more money in your own pocket you saved on the extra interest you woul

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

have paid. Put your debts in order of interest rate, the highest having the most urgent priority to the lowest.

The Psychology of Using Cash

We

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

live too much in a “plastic, cashless” society, banking institutions have made it too convenient for us to pay for items with the simple swipe of

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

card, it slips our attention just how much we’ve shelled out by the time we get to the fourth credit card purchase for the day. The risk of payin

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

with credit is the tendency to spend what you don’t have.

Pay credit card payments, bills and groceries using cash instead of credit, the more yo

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

u spend using cash and physically handling it, the better. It gives a sense of psychological perspective on how much you’re actually spending.

Fo

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

example, it’s much easier to realize you’ve spent $100 in cash when you’re counting the bills in your hands rather than with a few electronic swip

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

s of your card. You have more thought for the “hard earned” dollar you worked for when you’re forking it over to the shopkeeper for your groceries

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

.

Stores reward cash buyers and give them greater purchasing power and bigger discounts so there are great benefits to using cash.

Do not procras

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

inate debt interest. Use cash and you’ll not only be debt free quicker but have a deeper appreciation for the hard work it took to earn that money

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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