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Due primarily to their larger size and higher center of gravity, SUVs are more likely to roll over and sustain serious

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

roof damage, injuring or killing the vehicle occupants.

According to a recent study by the Insurance Institute for H

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ighway Safety, the number of deaths associated with side-impact accidents decreased by almost half when auto manufactu

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

rers lowered the height of the SUVs by as little as half an inch and/or included impact bars beneath the bumpers of th

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

vehicles.

As early as 1988, in a report issued jointly by Consumers Union and the Center for Auto Safety, the Suzuki

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

Samurai, a small SUV, was linked with an increased rate of rollover accidents. Since that time, the evidence has moun

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ted considerably that many SUVs on the market are disproportionately likely to tip and roll over during an accident, t

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

hus increasing the incidence of serious injuries and fatalities.

In a survey of 1996 data, 53% of fatal SUV crashes i

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

volved a rollover, compared to only 19% of fatal crashes in regular passenger cars. While many and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

http://www.rwklaw.com/suv_rollover_accidents.shtml">fatal SUV accidents result in the death of occupants of other

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

vehicles involved in a crash, SUV drivers and passengers were shown in a 2004 study to be 11% more likely to be killed

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

in an automobile accident than those in traditional passenger cars.

Despite the evidence, the National Highway Traff

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

c and Safety Administration (NHTSA) abandoned efforts to institute new rollover safety standards for SUVs and other li

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ght trucks in 1994, citing the costs to the automotive industry in having to comply with new design standards.

SUV Sa

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

fety Standards

Even though SUVs are frequently chosen by consumers to serve as passenger vehicles, SUVs are classifie

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

d as light trucks, which are subject to lower safety standards than traditional passenger cars.

SUVs require less pro

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ection from side-impacts and roof crush than even lighter passenger cars.

SUVs also frequently have more rigid constr

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

uction and less bumper reinforcement, which may increase injuries to both the SUV occupants and other accident victims

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

.

What to do

If you or someone you care about has been injured in an SUV accident involving a rollover or roof crush

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

damage, seek the advice of an experienced personal injury attorney as soon as possible to preserve all of your rights

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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