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    Turkey's steadily growing economy, large young population, increasing number of more affluent consumers and an ongoing housing shortage are all important factors to
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    consider when that country's real estate sector. Turkey's real estate investments were 1.1 billion USD in 2006, and the market is due to grow to 4 billion USD in 2
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    07, according to the Wall Street Journal.

    Istanbul has significant importance for the real estate investment boom in Turkey. Istanbul has a population of around 14
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    million, and with a 35% share of the Gross National Product (GNP) of Turkey it is a substantial commercial and cultural hub in the region. The city physically repre
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    ents only 0.7% of the Turkey’s total surface area and yet Istanbul has 31% of the country's total housing stock. Istanbul recently topped an Urban Land Institute /
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    WC survey for the best development prospects, leaving behind 26 significant markets including Moscow, London and Barcelona.

    Due to high population growth and incre
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    asing urbanisation rates, the demand for residential housing is climbing rapidly, and shows no signs of a slowdown in the near future. The Turkish construction sect
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    r has registered quarterly average growth rates of 21.2% since 2005, a figure which is substantially above the GDP growth of the country. The construction boom help
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    d the housing gap to decline significantly, however there is still a deficit of 150,000 units per year. Prices have risen 100 per cent in two years in Istanbul. Buy
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    ng an apartment flat cost ?2,500 per m2 in the city centre and ?2,000 per m2 in the satellite towns around the city. Istanbul property is expected to generate on av
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    rage 8% rental yields and 12.5% capital growth annually.

    Most of the recent Istanbul city developments have been of mixed-use - consisting of a combination of shop
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    ping centres, office buildings, luxurious city residential apartments and hotels targeting the upper and international market. Apartment flats for this type of uppe
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    market apartments and villas range from ?2.500 per m2 to ?6,000 per m2.

    The 179 apartments located in the flagship Kanyon shopping/residential complex - completed
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    in 2006 - are the latest example of a mixed-use project on a grand scale. The one-bedroom flat resale value is now ?350,000 - double their original price. Kanyon is
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    an open-air emporium shopping area replicating a natural canyon in form, creating natural cooling air flow. This is a complex that includes a four-level shopping ce
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    tre, 26-story office building and nine-screen cinema. It has 160 shops selling mainly luxury international products and brands such as Harvey Nichols and Hakkasan -
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    opening its first restaurant outside London - occupy three floors.

    The growing economy of Turkey and the increased income level amongst the young population is le
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    ding to more investment, especially in shopping malls. Istanbul has 39 modern shopping centres of which 22 were built after the year 2000. There are 16 more shoppin
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    malls under construction.

    With this seemingly never-ending list of projects similar to Kanyon either on the drawing board or actually under construction, the real
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    estate boom seems set to continue. Not just a city of mosques and bridges any more, Istanbul should be a serious port of call for property prospectors and investors


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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