Actual - Real Estate

For those who thought the term 'location' meant convenience to your daily routines, it is much more than that. It implies the constantly-changing effects upon a specific home or proper

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ty, caused by other people and the natural environment. Your concern should be pinpointed against other people – what type of people are your prospective neighbors? The viewing appoint

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ments will probably take place during office hours when neighbors are at work or school, but how does the neighborhood change in the evening? Are there people in the area who make life

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

unpleasant at night? Do many people work shifts, coming into the area during unsociable hours and waking up everyone else? Any location requires a careful survey to allow assessment of

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

the pros and cons; after all, you're investing a large amount of your money in this.

A certain amount of caution is required when undertaking the following exercise; I can't advise o

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

specific locations and each one is unique. What I wish to do is suggest various ways by which you can thoroughly assess a location, so here's my next tip:

# 2: Bring a 'prop' when yo

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

u visit your intended neighborhood and avoid inspecting it alone. Nothing draws more attention than a solitary adult loitering around an area and , in some countries, this is illegal.

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

Look at it from the neighbor's point of view; they are protecting their family and property against possible threat and can't tell from glancing at you that your motives are innocent.

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ou don't want to draw adverse attention to yourself or have the neighbors phone the police because you look suspicious. What do I mean by a prop? It could be a partner or friend, prefe

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

rably from the opposite sex if you are male (two men together make people suspicious since their first thoughts are you are 'casing' their home before breaking and entering). If you ha

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

e a child, bring him/her along (but avoid bringing several at the same time since they might attract too much attention - ration them out for subsequent trips if they are keen to accom

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

pany you).

An accompanied child often attracts positive attention from strangers, and may be a good way to introduce yourself to a prospective neighbor or for you to ask useful questi

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ons once you have explained that you're checking the neighborhood. Another useful prop is a dog (providing you bring a bag in case it fouls the path/sidewalk!). Like a child, a dog all

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ws you to pass slowly through an area, paying attention to detail and innocently surveying the scene. Where possible and safe, examine on foot, rather than arrive in a car, eve if it m

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

eans parking in a car park some distance away. For those who cycle, this is a non-invasive way to arrive and spend a little time without drawing undue attention. You can feign a mechan

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

cal problem and spend some time on the path/sidewalk 'fixing' your bicycle. If you can adapt or combine these props, you can make several visits to your location. Always bring a brochu

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

re/prospectus of the intended property which you can produce to demonstrate that you are a genuine prospective buyer.

Such surveys will yield a lot of useful information about an area

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

that you might have missed by visiting during office hours. It allows you to take an informed decision about an area, to privately decide which factors might affect your quality of li

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

e and to use any adverse effects as bargaining power when negotiating with the property's owners.

In the next installment I will suggest less direct ways of exploring a potential neig

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

hborhood and gathering important information about your future home, once you decide that an area still attracts you.

If you found these suggestions useful, please explore my websites

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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