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    The mortgage market has changed considerably over the last 20-25 years. Up until that time the main lenders were the Building Societies which, as mutual institutions, gave preference to their members, or to
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    those who had savings invested with the Society. The market is now almost unrecognizable from those days of only a quarter of a century ago.

    The prime lenders are now:

    Banks

    Where once the Banks had a ver
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    low profile in the mortgage market place, they now actively and aggressively encourage this type of business. As larger institutions, they are able to acquire funds cheaper and improve profit margins. By v
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    rtue of their large existing customer base, they know which would present a low potential risk and therefore, who to target for their services. A mortgage customer is, potentially, a long term customer, ofte
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    25 years or more, which gives an ongoing opportunity to cross sell a wide range of financial products – insurance, life assurance, pensions etc. Some of the larger traditional Building Societies have acquir
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    d bank status in recent times.

    Building Societies

    Building Societies have the longest history in the provision of property acquisition loans having been around since the late 18th. century. They set out as
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    mutual institutions owned by the members and quickly established themselves in the industrial parts of England during the industrial revolution. It was only in 1986, with the passing of the Building Societie
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    s Act, that the societies were permitted to diversify from lending only on freehold and leasehold property into other areas such as banking services and unsecured lending. Of their total lending portfolio, 7
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    % must still be for residential mortgages but should they convert to PLC status they may operate with the same freedom as the banks. As we know, many have opted to do so. Most Building Societies, however, st
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    ll remain as specialist lenders to the residential market.

    Specialised Mortgage Houses

    In the main these are limited companies that are either independent mortgage providers or are subsidiaries of larger f
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    nancial institutions such as banks. These companies developed out of the growth years of the late 1970s and early 1980s and are funded primarily from the wholesale market. They operate on a centralised basis
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    often with few or no branches.

    Insurance Companies

    Traditionally life companies have enjoyed only a small sector of the mortgage market, the prime target being the sale of related products such as life as
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    urance, endowment policies, pension plans etc. Some companies were heavily involved in the sale of top-up mortgages. This occurred where a Building Society would only be prepared to lend a certain percentage
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    say 80%, of the purchase price. If the borrower required a loan of, say, 90% of the purchase price the life company would advance the balance by way of a top-up. As the mortgage business has intensified and
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    become more competitive, the insurance companies have lost ground. However they still have a huge and significant role to play in the provision of mortgage related products.

    Finance Houses

    These companies
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    again often subsidiaries of the major banks, have offered finance facilities for home improvements, house extensions, conservatories etc. and enjoy a particular niche in the 2nd Mortgage, secured and unsecu
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    ed loans arena.

    There is one thing common to all the lenders. The trading attitudes of the friendly societies, providing a service to their members now rarely exists. The prime motivation is now profit. Pro
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    it for the shareholders, for the members, for the companies and, through their incomes and employment packages, for the directors and employees.

    It would be naive to continue to believe that, by agreeing to
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    grant us a mortgage to enable us to purchase a property, the lenders are doing us a favour out of some charitable sense of helping their fellow man! It is up to us therefore to treat these negotiations as w
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    would any other trade transaction and that means – shop around, haggle, seek advice, read the small print. In other words, do not be hassled into making a quick decision that involves any kind of commitment


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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