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Spain is one of Europe’s most popular tourist destinations; furthermore the attraction of Spain’s climate, culture, beauty, cost and standard of living attracts record numbers of expatriates to relocate to its shores every year and the country already has an es

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

timated 1.5 million foreign residents in situ.

But there’s a darker side to moving abroad that few people ever consider – did you know that last year 191,000 people relocated overseas from the UK…and 105,000 Britons also returned to the UK last year having fai

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

led to establish their new life overseas?

Some people simply fail to survive a move overseas and it certainly isn’t a case of “no going back” for the thousands of disillusioned people who flock ‘home’ to their mother country year after year…therefore if you’re

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

thinking of moving to Spain you need to understand the main reasons people cite when they return. By understanding these reasons you will avoid the pitfalls and pain and succeed where others may fail thereby fulfilling your dreams of a new life in Spain.

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

The Practicality of Your Location

You need to make sure that you choose the very best location in Spain to fulfil your practical needs on a day to day basis.

Consider the accessibility of a location for family and friends to visit you and for you to reach

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

a doctor, the supermarket, a school or even a hairdresser. Find your perfect location, location, location by visiting the areas you’re interested in and considering them thoroughly from the point of view of how easy and practical your day to day life there wi

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ll be.

Accessibility & Homesickness

Wherever you choose to live, consider the accessibility of the location with your old home country in mind. Sure, you may be sick of the sight of certain people right now but you never know what tomorrow will bring

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

and how are you going to feel if you can’t get back to visit, or if the important people in your life can’t afford to visit you?

Spain is very well serviced by airports and cheap airlines, it has one of the cheapest rail networks in the whole of Europe and the

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

Spanish government spends millions each year on the travel and transport infrastructure so wherever you choose to locate you should never be so far away from decent transportation. But do bear this point in mind as ‘homesickness’ and ‘inaccessibility’ are som

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

e of the main reasons people cite when they give up on their dream of a new life abroad.

Being Accepted

The first two years in any new country are by far the hardest…it takes this amount of time to build up enough knowledge of the local areas, customs,

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

people and language to make your new house feel like ‘home’.

It also takes a significant investment and effort on your part to find true acceptance and getting to the stage where you really feel you ‘belong’ in your Spanish community will take time, effort an

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

d above all perseverance.

Expectation versus Reality

Moving abroad won’t necessarily ‘fix’ your life - if you do move abroad you won’t escape your history, you won’t escape who you are, you won’t escape all of the day to day grind and you may not alway

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

s improve your quality of life! So make sure you have realistic expectations of your new life in Spain before you go and know that living in Spain will be very different to holidaying in Spain.

YES your new life abroad can offer you so much more …but just mak

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

e sure your expectations can match the reality and remember the saying – life isn’t necessarily a beach just because you live beside one!

Health & Wellbeing

One of the saddest reasons people cite when giving up their dream of a new life abroad is healt

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

h and wellbeing. The trap is the price, availability and quality of health care in their ‘new’ country. Please look at the local Spanish health care facilities, think about long term and respite care, consider health insurance for all your family and basicall

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

y don’t bury your head in the sand! If you consider the worst case scenario and protect yourself against it, chances are you will be prepared for everything and will financially survive.

Last But Not Least - Money

THE most common reasons for people re

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

turning ‘home’ with their dreams shattered is that they simply run out of money.

If you’re moving to Spain and hoping to find work you need to know that unemployment in the country is way above the EU average, if you don’t speak Spanish you’ll struggle and som

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

e of your qualifications may not be recognised in Spain. If you’re considering downsizing when you move to Spain it can be more than just a shock to the system to leave a well paying job to become a pool cleaner. If you’ve sold up and released equity to live

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

on have you honestly thought about how long you can practically live on this amount? What about affording your retirement years, trips back to your home country, health care, transportation and the unexpected costs that spring up when we least expect them?

Th

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ere are ways to afford to live on less and there are ways to make what you have go far further. The bottom line is - to survive in Spain you simply MUST consider your financial position before you make ANY move.

Good luck in realising and securing your dream.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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