Actual - Writing and Speaking

FORWARD

The 188 stage Hero's Journey (Monomyth) is the template upon which the vast majority of successful stories a

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

nd Hollywood blockbusters are based upon. In fact, ALL of the hundreds of Hollywood movies we have deconstructed (see

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

URL below) are based on this 188+ stage template.

Understanding this template is a priority for story or screenwrit

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

rs. This is the template you must master if you are to succeed in the craft.

[The terminology is most often metaphor

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ic and applies to all successful stories and screenplays, from The Godfather (1972) to Brokeback Mountain (2006) to A

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

nnie Hall (1977) to Lord of the Rings (2003) to Drugstore Cowboy (1989) to Thelma and Louise (1991) to Apocaplyse Now

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

(1979)].

THERE IS ONLY ONE STORY

THE 188 STAGE HERO'S JOURNEY:

a) Attempts to tap into unconscious e

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

xpectations the audience has regarding what a story is and how it should be told.

b) Gives the writer more structura

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

l elements than simply three or four acts, plot points, mid point and so on.

c) Gives you a tangible process for bui

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ding and releasing dissonance (establishing and achieving catharses, of which there are usually four).

d) Tells you

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

what to write. For example, at a certain stage of the story, the focus should be on the Call to Adventure and the mic

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ro elements within.

ABRIDGED TIPS, EXCERPTS AND EXAMPLES:

(simply go to dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ney.info/">http://www.heros-journey.info/ for full details)

*****No Mans Land*****

The Period of No Commitment

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

(before embarkation of the Trials) takes place in a No Mans Land. In Thelma and Louise (1991), both heroines sit it o

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ut in a hotel while they wait for Thelma to make a decision. In Bonnie and Clyde (1967), Clyde and his brother decide

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

what they’re going to do in the house.

*****Push into the Inner Cave*****

Pushes and Pulls are an underrated aspect

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

of storytelling. Pushes and Pulls force the Hero et al from one stage of the journey to the next.

A pull or push of

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

some sort will drive the Hero into the Inner Cave. This is where the Hero confronts (but does not conquer his Inner

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

hallenge) hence it is not unusual to encounter resistances or obstacles to the Inner Cave. Again, resistance to chang

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

e is natural. In City Slickers (1991), Mitch talks about being able to look at a Picasso but not take it off the wall

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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