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    FORWARD

    The 188 stage Hero's Journey (Monomyth) is the template upon which the vast majority of successful stories and
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    Hollywood blockbusters are based upon. In fact, ALL of the hundreds of Hollywood movies we have deconstructed (see URL
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    below) are based on this 188+ stage template.

    Understanding this template is a priority for story or screenwriters. T
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    his is the template you must master if you are to succeed in the craft.

    [The terminology is most often metaphoric and
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    pplies to all successful stories and screenplays, from The Godfather (1972) to Brokeback Mountain (2006) to Annie Hall
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    (1977) to Lord of the Rings (2003) to Drugstore Cowboy (1989) to Thelma and Louise (1991) to Apocaplyse Now (1979)].

    <
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    b>THERE IS ONLY ONE STORY

    THE 188 STAGE HERO'S JOURNEY:

    a) Attempts to tap into unconscious expectations t
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    he audience has regarding what a story is and how it should be told.

    b) Gives the writer more structural elements than
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    simply three or four acts, plot points, mid point and so on.

    c) Gives you a tangible process for building and releasin
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    g dissonance (establishing and achieving catharses, of which there are usually four).

    d) Tells you what to write. For
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    example, at a certain stage of the story, the focus should be on the Call to Adventure and the micro elements within.

    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    ABRIDGED TIPS, EXCERPTS AND EXAMPLES:

    (simply go to http://www.
    eros-journey.info/ for full details)

    *****Middle Cave Trial*****

    The Middle Cave, whichever it is (First Threshol
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    d, Road of Trials or beyond) is where the Hero confronts Allies and Enemies. A Trial is not unusual. In Straw Dogs (197
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    1), David finds it hard to work, drives to town and is nearly involved in a car accident, which he skillfully avoids.

    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    *****Conscious Agreement*****

    The Hero consciously agrees to Journey and Transform, post the Unbearable Antagonism. Me
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    hods include:

    Explicit Statement. An Explicit Statement or Declaration of Intent is heard. In The Matrix (1999), Neo h
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    as a choice between the blue and red pill. In Star Wars (1977), Luke explicitly states that he wants to join Obi Wan an
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    d become a Jedi Knight like his father.

    Implicit Statement. Even if the Hero is unwilling, the Explicit Statement may
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    be implicit in the Hero's action. In Gladiator (2000), Maximus' family has been brutally murdered. He will seek revenge


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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