Actual - Communications

Millions of people all over the world connect to the Internet each day through ISPs (Internet service providers). Most people know what type of connection they have: dial-up, cable, DSL or satellite—some connections are high-speed/broadband

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

(the terms are interchangeable) while others aren’t.

While the average Internet consumer knows the name of their connection type, few know much more. When you explore the assets and liabilities of each ISP method, you can best choose the

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

Internet connection that will fit your household habits best.

Dial-up ISP
Dial-up is a connection that sends information through the phone line by way of a modem. Some dial-up ISPs offer accelerators that use content compressio

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

n and page caching to increase the speed of the data transfer. If you have a phone line, you can generally find a dial-up ISP in your area.

Dial-up ISP:
• Typical speed of 56K per second
• Uses the telephone line; you can’t call

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

and surf the Internet simultaneously (without an additional line)
• Requires a phone line
• Usually the least expensive

Cable ISP
A cable Internet provider offers Internet service through the same coax cable throu

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

gh which you receive cable television. Currently, cable is the fastest of all connections, but speeds can be affected by the number of local customers connected at the same time. A cable connection requires a modem that can be rented from t

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

he ISP or purchased from a local computer dealer.

Cable ISP:
• Is always on so there is no need to wait for a lengthy dial-up connection
• Is 50 times faster than a typical dial-up connection
• Allows you to use the telephon

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

e and Internet at the same time
• Requires a cable connection

DSL ISP
Digital Subscriber Line (DSL), like a dial-up connection, comes through your phone line, but DSL uses electrical signals at frequencies that humans

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

cannot hear. Many phone companies offer DSL connection at discounted prices if you also use their phone services. There are two main differences between DSL and dial-up: first, DSL is much faster (up to 50 times) and second, because you can

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

not hear the data signal, you can use your phone and the Internet at the same time even with only one phone line.

DSL ISP:
• Is always on so there is no need to wait for a lengthy dial-up connection
• Is 50 times faster than typi

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

al dial-up connection
• Allows you to use the telephone and Internet at same time
• Requires a phone line, a filter, and a data sending/receiving box that translates data
• You must be in the phone company’s DSL service area

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

since these delicate transmission frequencies deteriorate over a short distance.

Satellite ISP
Satellite is a connection that makes high-speed Internet accessible to areas where DSL and cable connections are not yet available.

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

Data is downloaded (received) about 10 times faster than dial-up through a satellite dish attached to your home. Some satellite systems have slower uploading times (sending data) because data must travel over phone lines through a modem. Ot

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

her systems use the satellite both ways—for uploading and downloading.

Satellite ISP:
• Is always on so there is no need to wait for a lengthy dial-up connection
• Is usually 10 times faster than typical dial-up connection
•

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

Allows you to use telephone and the Internet at same time
• Does not require a cable line
• Is very expensive to set up; an Internet satellite dish and satellite modem are required.
• Some satellite providers penalize you fo

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

r frequent downloads and uploads with a megabyte limit ; this should appear in the fine print of your contract, so read carefully and ask questions

Wireless ISP
Wireless is an Internet connection offered by businesses with

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

access to a main Internet route. Data is downloaded about 50 times faster than dial-up through a direct line-of-sight (LOS) from your home to the provider’s antenna. You must have a powered receiving antenna on your property to send and rec

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

eive data.

Wireless ISP:
• Is always on so there is no need to wait for a lengthy dial-up connection
• Is usually 50 times faster than typical dial-up connection
• Allows you to use telephone and the Internet at same time

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

> • Does not require a cable line
• May cost a few hundred dollars to set up; an antenna with power is required
• You must be able to see the provider’s antenna from your antenna for the connection to work—hills, trees and buildi

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ngs blocking the view will cancel the connection

Whether you live on the Internet and like to surf at break-neck speeds or are looking for an Internet provider that offers a cost-effective service—there is an ISP that’s perfect for you

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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