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    I still remember it very clear ... It was almost a decade ago that I wrote it in my notebook as an interesting quotation fro
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    m a famous man at that time and even now and ever. Mikhail Gorbachev, Soviet president, shared this so-called joke with some
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    reporters: "Mitterand has 100 lovers. One has AIDS, but he doesn't know which one. Bush has 100 bodyguards. One is a terror
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    ist, but he doesn't know which one. Gorbachev has 100 economic advisers. One is smart, but he doesn't know which one!"

    Afte
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    r all these years, After I found it and read it again, noticed how interesting it can be when we expand and continue it with
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    the notion of web and marketting via web sites and/or e-mails. Yes, according to your log files, you have 100 visitors for
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    your web site. One is a buyer, but you don't know which one! You just have to wait and see ... In your site, you have 100 we
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    b pages with 100 images. One page is missing one single image and you don't know which one. You miss 100 visitors only becau
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    se of this little mistake and WOW! On the Internet, you receive 100 "I Love You" e-mail messages a day, one has a killing vi
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    rus, but you don't know which one! You have 100 links in your directory. One is expired and/or out-of-date, but you don't kn
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    w which one and this may reduce the number of your hits and your visitors. You have a mailing list with 100 subscribers. One
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    is now reading your editorial and you don't know which one, because you don't receive any feedback. This may make you sad o
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    r disappointed! But who cares! You have 100 web sites. One will be a successful one and will make a rich man out of you, but
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    you don't know which one.

    I have 100 dreams a day for the success of my newsletter in Webfaqt.com. One is so great but I d
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    on't know which one. Isn't it interesting, I mean the Internet and Webfaqt? This is why, you are kindly invited to share it
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    with others, to continue this article with your own sentences. In my newsletter, we have enough room for your thoughts and v
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    iews. Anyway, I also have to thank Mr. Gorbachev for the joke...

    Use the best on-line and off-line tools to re-check your i
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    ncoming and outgoing web pages and e-mails to reduce the number of errors you may encounter while you are designing web sit
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    es, creating web pages, sending and receiving e-mails. Subscribe accredited guide newsletters warning you of outbreaks of n
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    ew viruses and even hoax messages. Educate yourself and your friends with the latest tips, tools and trends of the Internet


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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